NEO sarms - MK-677/Ibutamoren General Description
Ibutamoren (the lab code of the drug is MK-677) is a potent non-peptide ghrelin receptor agonist with a long period of activity in the body. The active agent stimulates the production of somatotropin. The drug is a potent natural growth hormone and IGF-1 production stimulant. It also has a stimulating effect on metabolic processes. With cycle use, it increases bone density. Ibutamoren has a positive effect on brain activity and the central nervous system.
The unique property of the drug is based on the fact that an increase in the production of substances that include somatotropin and IGF-1 does not result in an increase of the concentration of cortisol. The drug changes the metabolic processes of fat cells, which allows users to quickly burn fat and makes Ibutamoren an indispensable drug for lean muscle mass gain without setbacks. The substance produces an effect on the body similar to taking somatotropin, but the price of the drug for a cycle is cheaper than the use of recombinant somatotropin, and it’s safer for health.
NEO sarms - MK-677/Ibutamoren Benefits
Various athletes use Ibutamoren to increase muscle volume and strength, improve endurance and performance and reduce fat. The drug is commonly used by professional bodybuilders and amateurs in the field of body improvement. The main advantage of using Ibutamoren is that it does not change the functioning of the body, does not replace the natural hormone with a synthetic one, but accelerates the production of natural growth hormone, which has many beneficial effects. Somatotropin is characterized by a strong anabolic effect and stimulated lipolysis.
The positive properties of Apoxar Ibutamoren include its ability to:
- stimulate the production of natural somatotropin;
- stimulate the production of insulin-like growth factor 1;
- build up lean muscle mass;
- improve strength performance;
- improve bone tissue strength;
- improve endurance;
- stimulate fat burning;
- stimulate metabolism;
- improve protective functions of the body, strengthen immune system;
- improve sleep;
- accelerate healing processes;
- restore injured ligaments and tendons;
- increase overall vitality.
Scientific testing of the impact of Ibutamoren on the human body found that a single administration of the drug at a dosage of 25 mg produces an average peak concentration of somatotropin equal to 22.1 mcg/l. Large doses of the active agent result in even higher concentrations of somatotropin. Ibutamoren retains the concentration of growth hormone in plasma, which allows somatotropin to be produced evenly.
Regular use of the drug makes it possible to increase the concentration of insulin-like growth factor 1 by 39-89% of the initial values. Apoxar MK-677 affects several brain regions responsible for metabolic processes. It acts in various ways:
- reduces the concentration of somatostatin, which is a peptide hormone, and its effect is to suppress the production of somatotropin;
- increases the production of the GHRH hormone, which stimulates of the production of somatotropin in the anterior pituitary;
- assists signals in the pituitary GHRH hormone;
- blocks signals of somatostatin receptors.
By increasing the concentration of somatotropin, MK-677 increases muscle volume, improves strength and reduces body fat. The drug has the ability to reduce muscle loss, increase muscle strength and speed of walking (this effect is especially noticeable among older people) and increases bone mineralization. Studies have shown that Ibutamoren increases the duration of sleep and the quality of night rest, which contributes to better health. The drug does not have an androgenic effect on the body, so female athletes can safely use it without the risk of developing secondary male sexual characteristics.
NEO sarms - MK-677/Ibutamoren Possible Side Effects
The active agent does not cause adverse reactions. During the use of the drug, athletes may feel numbness of the upper limbs and fingers; feelings of fatigue; slight increase in appetite. These reactions are characteristic of an increased concentration of somatotropin, which indicates the effectiveness of the drug, but such symptoms may not occur in all users. Akin to the action of growth hormone, Ibutamoren can cause fluid retention in the body. This problem is solved by adjusting the diet or via the use of diuretics.
NEO sarms - MK-677/Ibutamoren Administration and Dosage
The effectiveness of using Ibutamoren does not depend on age, gender and other physical characteristics of the user. Daily dosages of 25 mg are comparable to the injection of recombinant somatotropin. Athletes weighing up to 80 kg are required to take one capsule (25 mg of the drug is contained in one pill) once a day at bedtime on an empty stomach (if evening use of the active agent interferes with sleep, the capsule should be consumed in the morning on an empty stomach before eating). MK-677 can cause drowsiness, so it is advisable to consume the capsule before bedtime.
Athletes weighing more than 80 kg need to use 2 capsules per day – one in the morning before a meal on an empty stomach and a capsule at bedtime. The duration of somatotropin production activation after a single use of the drug lasts for 8 hours or more. This duration of production of growth hormone is effective for enhancing the secretion of IGF-1.
NEO sarms - MK-677/Ibutamoren Combined Cycles
To increase muscle volume, Ibutamoren can be used during a solo cycle and in combination with Ostarine, Radarine and LGD-3303. The duration of the combined cycle should not exceed 8 weeks. To stimulate the reduction of body fat, the drug must be combined with Reverol or Cardarine, the duration of the cycle should not exceed two months.