Isotretinoin is primarily used as a treatment for severe acne. The most common adverse effects are a transient worsening of acne (lasting 1–4 months), dry lips cheilitis dry and fragile skin, and an increased susceptibility to sunburn. Uncommon and rare side effects include muscle aches and pains myalgias and headaches. Isotretinoin is known to cause birth defects due to in-utero exposure because of the molecule’s close resemblance to retinoic acid, a natural vitamin A derivative which controls normal embryonic development. It is also associated with psychiatric side effects, most commonly depression but also, more rarely, psychosis and unusual behaviours Other rare side effects include hyperostosis and premature epiphyseal closure, have been reported to be persistent.
Arimidex is an extremely powerful anti estrogen medication which is very beneficial to athletes taking aromatizing steroids. If an athlete is prone to US region base side effects, Arimidex can work as a full estrogen blockade which can prevent the buildup of estrogen throughout the body.
In order to find the correct dosage for Arimidex it's recommended to take Salvatori tests for blood tests after the first week to ensure that you are getting enough of this aromatase inhibitor. Arimidex essentially prevents the process of converting steroids into estrogen making this medication work a little bit differently than Nolvadex and Clomid which block the receptors in some tissues while activating receptors in other parts of the body.
The recommended dosage on Arimidex is .5 to 1 mg each day.
Nolvadex is a selective estrogen blocker which can prevent negative estrogen-based side effects from the build of the vestry and throw your body. The way that this medication works is by preventing estrogen from acting upon certain receptors in our body which can prevent negative side effects such as water retention and gyno for athletes that are utilizing aromatizing steroids like testosterone.
Nolvadex works to redistribute the testosterone in the body and stimulates LH production which can provide a big benefit after an athlete is finished some type of steroid cycle. Taking doses of tamoxifen in a PCT program for 4 to 6 weeks can ensure that the body chemistry normalizes and then all of the games that an athlete makes over their cycle can remain permanent. In most cases athletes will take the medication with their cycle and then shortly after the cycle.